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Bing Sun
NYU Bioinformatics Group,
715 Broadway, Rm 1008
New York, NY 10003
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Phone: 212 998 3366
Fax: 212 998 3337
e-mail:bingsun [at]
cs.nyu.edu
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Research Interest
I joined Prof. Nad Seeman's research group
in 1999 and recieved my Master degrees of Chemistry in Chemistry Dept.
from NYU in 2001. Then I switched to Computer Science Dept. and got Master
degree of Computer Science in Computer Science Dept. from NYU in 2002.
Currently I am working towards my PhD degree in Computer Science in Prof.
Bud Mishra's Bioinformatics group. The primary goal of computational
molecular biology, like molecular biology itself, is to understand the
meaning of the genomic information and how this information is expressed.
I am interested in applying bioinformatics to practical problems of
international significance and facilitating genome-based research through
the development and maintenance of biological software and
databases.
Current Projects
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Genome Annotation Project:
Performed analytical calculations of sequence-dependent
melting stability of duplex DNA based on the
nearest-neighbor model. The physical-thermal-stabilty property of human
genomic DNA double-helix can be described by the complete physical
annotation on human genome. |
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EST Alignment:
Researching BLAT, BLAST alignment algorithms to perform large-scale DNA sequence alignment. Aligned human ESTs against human genome by building BLAT client-server batch work system in a Linux cluster consisting of Scali system. |
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EST Classification:
Improving the C++ chromosome viewer tool in VALIS to visualize the alignments between human genome and ESTs; Classifying the ESTs into various groups based on their physical properties, the genetic functions of the aligned compartment, and cross-species sequence conservation. |
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Statistical Sequence Analysis:
Performing statistical tests like ANOVA tests for the classified human ESTs. The statistical analyses include physical properties analysis, word frequencies analysis, codon usage bias analysis, cross species sequence conservation analysis and etc. |
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Molecular Physiology Modeling:
Modeled giant squid axon action potential propagation using the spatial Hodgkin Huxley Model and simulated the giant barnacle muscle fiber using Morris-Lecar Model. Click here to see the movie of squid axon action potential propagation. |
Background
My resume in html, pdf, ps
Other LinksProf. Ned Seeman's
Home Page.
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